Abstract & Overview
Background and Objectives: In 2009, a strain of swine flu called H1N1 infected many people around the world. Cases of H1N1 also found in Gujarat. Panic in population, rapid spread from human to human and high CFR influence to study epidemiological features and factors those affecting outcomes which are helpful for controlling H1N1. So, the objective of this study is to study the epidemiologic features and clinical outcome among patients hospitalized in H1N1 ward, Sir T. Hospital Bhavnagar, Gujarat. Methods: Retrospective study was conducted of 134 suspected cases of H1N1 admitted from January 2010 to October 2012 at Sir T. Hospital Bhavnagar, Gujarat. Results: There were 79 males and 55 female admitted as a suspected H1N1 in hospital among them 24 males and 19 female found laboratory confirmed H1N1 positive. Most of the positive cases found in age between 20 to 45 years. Test positive rate among female (34.54%) higher than male (30.37%). Total 16 deaths were confirmed due to H1N1.CFR in female (57.89%) much higher comparing to male (20.83%). Most of the cases admitted with high grade fever (100%), Breathlessness (99%) and tachycardia (90%). The 24% cases developed acute respiratory distress syndrome (ARDS), of this 50% survived. Peak of cases found in winter and rainy season. Cases shows cyclical trend. Interpretation and Conclusion: High grade fever and breathlessness were the main presenting complaints. Tachycardia as clinical sign predicts development of respiratory complications. ARDS was observed to be the main cause of mortality in this study.