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Weighted Gene Coexpression Network Analysis: State of the Art

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Abstract & Overview

Weighted gene coexpression network analysis (WGCNA) has been applied to many important studies since its introduction in 2005. WGCNA can be used as a data exploratory tool or as a gene screening method; WGCNA can also be used as a tool to generate testable hypothesis for validation in independent data sets. In this article, we review key concepts of WGCNA and some of its applications in gene expression analysis of oncology, brain function, and protein interaction data.

Cite this record

Wei Zhao, Peter Langfelder, Tova F Fuller, Jun Dong, Ai Li, Steve Hovarth (2010). Weighted Gene Coexpression Network Analysis: State of the Art. Journal of Biopharmaceutical Statistics, 20(2), 281–300. https://doi.org/10.1080/10543400903572753

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Zhao, W., Langfelder, P., Fuller, T. F., Dong, J., Li, A., & Hovarth, S. (2010). Weighted Gene Coexpression Network Analysis: State of the Art. Journal of Biopharmaceutical Statistics, 20(2), 281–300. https://doi.org/10.1080/10543400903572753
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