Abstract & Overview
Background: Urinary tract infection (UTI) is one of the most common infectious diseases at the community level. To assess the adequacy of the empirical therapy, the prevalence and the resistance pattern of the main bacteria responsible for UTI in the rural community of Himachal Pradesh (HP) was evaluated. Methods: In this retrospective study, all urine samples from patients of the District of Solan, in HP, collected at the Department of Microbiology, Maharishi Markandeshwar Medical College and Hospital during 2014–15 were analyzed. Samples with more than 105 CFU/mL bacteria were considered positive, and for these samples, the bacteria were identified, and the profile of antibiotic susceptibility was characterized. Results: A retrospective analysis of 1878 urine samples over 2-year period at a teaching hospital was carried out according to the standard protocol of urinalysis. The results were processed to obtain the profile prevalence of UTI, the rate of bacterial resistance to antibiotics, the trend of their evolution over time, and the rate of multidrug resistance. Conclusion: Escherichia coli was the most common uropathogen. Amikacin and piperacillin/tazobactam were the most effective antibiotics against uropathogens.