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Periodicals

On-Line Building Energy Optimization Using Deep Reinforcement Learning

Unprecedented high volumes of data are becoming available with the growth of the advanced metering infrastructure. These are expected to benefit planning and operation of the future power systems and to help customers transition from a passive to an active role. In this paper, we explore for the first time in the smart grid context the benefits of using deep reinforcement learning, a hybrid type of methods that combines reinforcement learning with deep learning, to perform on-line optimization of schedules for building energy management systems. The learning procedure was explored using two methods, Deep Q-learning and deep policy gradient, both of which have been extended to perform multiple actions simultaneously. The proposed approach was validated on the large-scale Pecan Street Inc. database. This highly dimensional database includes information about photovoltaic power generation, electric vehicles and buildings appliances. Moreover, these on-line energy scheduling strategies could be used to provide realtime feedback to consumers to encourage more efficient use of electricity.

Architecture & Planning2018Institute of Electrical and Electronics Engineers
Periodicals

PyNN: a common interface for neuronal network simulators

Computational neuroscience has produced a diversity of software for simulations of networks of spiking neurons, with both negative and positive consequences. On the one hand, each simulator uses its own programming or configuration language, leading to considerable difficulty in porting models from one simulator to another. This impedes communication between investigators and makes it harder to reproduce and build on the work of others. On the other hand, simulation results can be cross-checked between different simulators, giving greater confidence in their correctness, and each simulator has different optimizations, so the most appropriate simulator can be chosen for a given modelling task. A common programming interface to multiple simulators would reduce or eliminate the problems of simulator diversity while retaining the benefits. PyNN is such an interface, making it possible to write a simulation script once, using the Python programming language, and run it without modification on any supported simulator (currently NEURON, NEST, PCSIM, Brian and the Heidelberg VLSI neuromorphic hardware). PyNN increases the productivity of neuronal network modelling by providing high-level abstraction, by promoting code sharing and reuse, and by providing a foundation for simulator-agnostic analysis, visualization and data-management tools. PyNN increases the reliability of modelling studies by making it much easier to check results on multiple simulators. PyNN is open-source software and is available from http://neuralensemble.org/PyNN.

Architecture & Planning2008Frontiers Media
Periodicals

Covalent Organic Frameworks as a Decorating Platform for Utilization and Affinity Enhancement of Chelating Sites for Radionuclide Sequestration

Abstract The potential consequences of nuclear events and the complexity of nuclear waste management motivate the development of selective solid‐phase sorbents to provide enhanced protection. Herein, it is shown that 2D covalent organic frameworks (COFs) with unique structures possess all the traits to be well suited as a platform for the deployment of highly efficient sorbents such that they exhibit remarkable performance, as demonstrated by uranium capture. The chelating groups laced on the open 1D channels exhibit exceptional accessibility, allowing significantly higher utilization efficiency. In addition, the 2D extended polygons packed closely in an eclipsed fashion bring chelating groups in adjacent layers parallel to each other, which may facilitate their cooperation, thereby leading to high affinity toward specific ions. As a result, the amidoxime‐functionalized COFs far outperform their corresponding amorphous analogs in terms of adsorption capacities, kinetics, and affinities. Specifically, COF‐TpAb‐AO is able to reduce various uranium contaminated water samples from 1 ppm to less than 0.1 ppb within several minutes, well below the drinking water limit (30 ppb), as well as mine uranium from spiked seawater with an exceptionally high uptake capacity of 127 mg g −1 . These results delineate important synthetic advances toward the implementation of COFs in environmental remediation.

Architecture & Planning2018
Periodicals

A Survey on Internet of Things From Industrial Market Perspective

The Internet of Things (IoT) is a dynamic global information network consisting of Internet-connected objects, such as radio frequency identifications, sensors, and actuators, as well as other instruments and smart appliances that are becoming an integral component of the Internet. Over the last few years, we have seen a plethora of IoT solutions making their way into the industry marketplace. Context-aware communications and computing have played a critical role throughout the last few years of ubiquitous computing and are expected to play a significant role in the IoT paradigm as well. In this paper, we examine a variety of popular and innovative IoT solutions in terms of context-aware technology perspectives. More importantly, we evaluate these IoT solutions using a framework that we built around well-known context-aware computing theories. This survey is intended to serve as a guideline and a conceptual framework for context-aware product development and research in the IoT paradigm. It also provides a systematic exploration of existing IoT products in the marketplace and highlights a number of potentially significant research directions and trends.

Architecture & Planning2014Institute of Electrical and Electronics Engineers
Periodicals

Intranasal Drug Delivery: How, Why and What for?

Over the recent decades the interest in intranasal delivery as a non-invasive route for drugs is increased.Since the nasal mucosa offers numerous benefits as a target tissue for drug delivery, a wide variety of therapeutic compounds may be administered intranasally for topic, systemic and central nervous system action. We have, herein, outlined the relevant aspects of nasal anatomy, physiology and histology, and the biological, physicochemical and pharmaceutical factors that must be considered during the process of discovery and development of nasal drugs as well as in their incorporation into appropriate nasal pharmaceutical formulations.

Architecture & Planning2009Canadian Society for Pharmaceutical Sciences
Periodicals

Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST

Spatial transcriptomics technologies generate gene expression profiles with spatial context, requiring spatially informed analysis tools for three key tasks, spatial clustering, multisample integration, and cell-type deconvolution. We present GraphST, a graph self-supervised contrastive learning method that fully exploits spatial transcriptomics data to outperform existing methods. It combines graph neural networks with self-supervised contrastive learning to learn informative and discriminative spot representations by minimizing the embedding distance between spatially adjacent spots and vice versa. We demonstrated GraphST on multiple tissue types and technology platforms. GraphST achieved 10% higher clustering accuracy and better delineated fine-grained tissue structures in brain and embryo tissues. GraphST is also the only method that can jointly analyze multiple tissue slices in vertical or horizontal integration while correcting batch effects. Lastly, GraphST demonstrated superior cell-type deconvolution to capture spatial niches like lymph node germinal centers and exhausted tumor infiltrating T cells in breast tumor tissue.

Architecture & Planning2023Nature Portfolio
Periodicals

Deep Learning for Safe Autonomous Driving: Current Challenges and Future Directions

Advances in information and signal processing technologies have a significant impact on autonomous driving (AD), improving driving safety while minimizing the efforts of human drivers with the help of advanced artificial intelligence (AI) techniques. Recently, deep learning (DL) approaches have solved several real-world problems of complex nature. However, their strengths in terms of control processes for AD have not been deeply investigated and highlighted yet. This survey highlights the power of DL architectures in terms of reliability and efficient real-time performance and overviews state-of-the-art strategies for safe AD, with their major achievements and limitations. Furthermore, it covers major embodiments of DL along the AD pipeline including measurement, analysis, and execution, with a focus on road, lane, vehicle, pedestrian, drowsiness detection, collision avoidance, and traffic sign detection through sensing and vision-based DL methods. In addition, we discuss on the performance of several reviewed methods by using different evaluation metrics, with critics on their pros and cons. Finally, this survey highlights the current issues of safe DL-based AD with a prospect of recommendations for future research, rounding up a reference material for newcomers and researchers willing to join this vibrant area of Intelligent Transportation Systems.

Architecture & Planning2020Institute of Electrical and Electronics Engineers
Periodicals

Evaluation of Sentinel-2 Red-Edge Bands for Empirical Estimation of Green LAI and Chlorophyll Content

ESA's upcoming satellite Sentinel-2 will provide Earth images of high spatial, spectral and temporal resolution and aims to ensure continuity for Landsat and SPOT observations. In comparison to the latter sensors, Sentinel-2 incorporates three new spectral bands in the red-edge region, which are centered at 705, 740 and 783 nm. This study addresses the importance of these new bands for the retrieval and monitoring of two important biophysical parameters: green leaf area index (LAI) and chlorophyll content (Ch). With data from several ESA field campaigns over agricultural sites (SPARC, AgriSAR, CEFLES2) we have evaluated the efficacy of two empirical methods that specifically make use of the new Sentinel-2 bands. First, it was shown that LAI can be derived from a generic normalized difference index (NDI) using hyperspectral data, with 674 nm with 712 nm as best performing bands. These bands are positioned closely to the Sentinel-2 B4 (665 nm) and the new red-edge B5 (705 nm) band. The method has been applied to simulated Sentinel-2 data. The resulting green LAI map was validated against field data of various crop types, thereby spanning a LAI between 0 and 6, and yielded a RMSE of 0.6. Second, the recently developed "Normalized Area Over reflectance Curve" (NAOC), an index that derives Ch from hyperspectral data, was studied on its compatibility with simulated Sentinel-2 data. This index integrates the reflectance curve between 643 and 795 nm, thereby including the new Sentinel-2 bands in the red-edge region. We found that these new bands significantly improve the accuracy of Ch estimation. Both methods emphasize the importance of red-edge bands for operational estimation of biophysical parameters from Sentinel-2.

Architecture & Planning2011Multidisciplinary Digital Publishing Institute
Periodicals

Industry 4.0 and Sustainability Implications: A Scenario-Based Analysis of the Impacts and Challenges

The new evolution of the production and industrial process called Industry 4.0, and its related technologies such as the Internet of Things, big data analytics, and cyber–physical systems, among others, still have an unknown potential impact on sustainability and the environment. In this paper, we conduct a literature-based analysis to discuss the sustainability impact and challenges of Industry 4.0 from four different scenarios: deployment, operation and technologies, integration and compliance with the sustainable development goals, and long-run scenarios. From these scenarios, our analysis resulted in positive or negative impacts related to the basic production inputs and outputs flows: raw material, energy and information consumption and product and waste disposal. As the main results, we identified both positive and negative expected impacts, with some predominance of positives that can be considered positive secondary effects derived from Industry 4.0 activities. However, only through integrating Industry 4.0 with the sustainable development goals in an eco-innovation platform, can it really ensure environmental performance. It is expected that this work can contribute to helping stakeholders, practitioners and governments to advance solutions to deal with the outcomes emerging through the massive adoption of those technologies, as well as supporting the expected positive impacts through policies and financial initiatives.

Architecture & Planning2018Multidisciplinary Digital Publishing Institute
Periodicals

Deep Generative Modelling: A Comparative Review of VAEs, GANs, Normalizing Flows, Energy-Based and Autoregressive Models

Deep generative models are a class of techniques that train deep neural networks to model the distribution of training samples. Research has fragmented into various interconnected approaches, each of which make trade-offs including run-time, diversity, and architectural restrictions. In particular, this compendium covers energy-based models, variational autoencoders, generative adversarial networks, autoregressive models, normalizing flows, in addition to numerous hybrid approaches. These techniques are compared and contrasted, explaining the premises behind each and how they are interrelated, while reviewing current state-of-the-art advances and implementations.

Architecture & Planning2021Durham University
Periodicals

Advancing Neuromorphic Computing With Loihi: A Survey of Results and Outlook

Deep artificial neural networks apply principles of the brain's information processing that led to breakthroughs in machine learning spanning many problem domains. Neuromorphic computing aims to take this a step further to chips more directly inspired by the form and function of biological neural circuits, so they can process new knowledge, adapt, behave, and learn in real time at low power levels. Despite several decades of research, until recently, very few published results have shown that today's neuromorphic chips can demonstrate quantitative computational value. This is now changing with the advent of Intel's Loihi, a neuromorphic research processor designed to support a broad range of spiking neural networks with sufficient scale, performance, and features to deliver competitive results compared to state-of-the-art contemporary computing architectures. This survey reviews results that are obtained to date with Loihi across the major algorithmic domains under study, including deep learning approaches and novel approaches that aim to more directly harness the key features of spike-based neuromorphic hardware. While conventional feedforward deep neural networks show modest if any benefit on Loihi, more brain-inspired networks using recurrence, precise spike-timing relationships, synaptic plasticity, stochasticity, and sparsity perform certain computation with orders of magnitude lower latency and energy compared to state-of-the-art conventional approaches. These compelling neuromorphic networks solve a diverse range of problems representative of brain-like computation, such as event-based data processing, adaptive control, constrained optimization, sparse feature regression, and graph search.

Architecture & Planning2021Institute of Electrical and Electronics Engineers
Periodicals

On the Inertia of Future More-Electronics Power Systems

Inertia plays a vital role in maintaining the frequency stability of power systems. However, the increase of power electronics-based renewable generation can dramatically reduce the inertia levels of modern power systems. This issue has already challenged the control and stability of small-scale power systems. It will soon be faced by larger power systems as the trend of large-scale renewable integration continues. In view of the urgent demand for addressing the inertia concern, this paper presents a comprehensive review of inertia enhancement methods covering both proven techniques and emerging ones and also studies the effect of inertia on frequency control. Among those proven techniques, the inertia emulation by wind turbines has successfully demonstrated its effectiveness and will receive widespread adoptions. For the emerging techniques, the virtual inertia generated by the dc-link capacitors of power converters has a great potential due to its low cost. The same concept of inertia emulation can also be applied to ultracapacitors. In addition, batteries will serve as an alternative inertia supplier, and the relevant technical challenges as well as the solutions are discussed in this paper. In future power systems where most of the generators and loads are connected via power electronics, virtual synchronous machines will gradually take over the responsibility of inertia support. In general, it is concluded that advances in semiconductors and control promise to make power electronics an enabling technology for inertia control in future power systems.

Architecture & Planning2018Institute of Electrical and Electronics Engineers
Periodicals

The International Reference Ionosphere 2012 – a model of international collaboration

The International Reference Ionosphere (IRI) project was established jointly by the Committee on Space Research (COSPAR) and the International Union of Radio Science (URSI) in the late sixties with the goal to develop an international standard for the specification of plasma parameters in the Earth’s ionosphere. COSPAR needed such a specification for the evaluation of environmental effects on spacecraft and experiments in space, and URSI for radiowave propagation studies and applications. At the request of COSPAR and URSI, IRI was developed as a data-based model to avoid the uncertainty of theory-based models which are only as good as the evolving theoretical understanding. Being based on most of the available and reliable observations of the ionospheric plasma from the ground and from space, IRI describes monthly averages of electron density, electron temperature, ion temperature, ion composition, and several additional parameters in the altitude range from 60 km to 2000 km. A working group of about 50 international ionospheric experts is in charge of developing and improving the IRI model. Over time as new data became available and new modeling techniques emerged, steadily improved editions of the IRI model have been published. This paper gives a brief history of the IRI project and describes the latest version of the model, IRI-2012. It also briefly discusses efforts to develop a real-time IRI model. The IRI homepage is at http://IRImodel.org.

Architecture & Planning2014EDP Open
Periodicals

An operational model for mainstreaming ecosystem services for implementation

Research on ecosystem services has grown markedly in recent years. However, few studies are embedded in a social process designed to ensure effective management of ecosystem services. Most research has focused only on biophysical and valuation assessments of putative services. As a mission-oriented discipline, ecosystem service research should be user-inspired and user-useful, which will require that researchers respond to stakeholder needs from the outset and collaborate with them in strategy development and implementation. Here we provide a pragmatic operational model for achieving the safeguarding of ecosystem services. The model comprises three phases: assessment, planning, and management. Outcomes of social, biophysical, and valuation assessments are used to identify opportunities and constraints for implementation. The latter then are transformed into user-friendly products to identify, with stakeholders, strategic objectives for implementation (the planning phase). The management phase undertakes and coordinates actions that achieve the protection of ecosystem services and ensure the flow of these services to beneficiaries. This outcome is achieved via mainstreaming, or incorporating the safeguarding of ecosystem services into the policies and practices of sectors that deal with land- and water-use planning. Management needs to be adaptive and should be institutionalized in a suite of learning organizations that are representative of the sectors that are concerned with decision-making and planning. By following the phases of our operational model, projects for safeguarding ecosystem services are likely to empower stakeholders to implement effective on-the-ground management that will achieve resilience of the corresponding social-ecological systems.

Architecture & Planning2008National Academy of Sciences
Periodicals

Modulation of the Root Microbiome by Plant Molecules: The Basis for Targeted Disease Suppression and Plant Growth Promotion

Plants host a mesmerizing diversity of microbes inside and around their roots, known as the microbiome. The microbiome is composed mostly of fungi, bacteria, oomycetes, and archaea that can be either pathogenic or beneficial for plant health and fitness. To grow healthy, plants need to surveil soil niches around the roots for the detection of pathogenic microbes, and in parallel maximize the services of beneficial microbes in nutrients uptake and growth promotion. Plants employ a palette of mechanisms to modulate their microbiome including structural modifications, the exudation of secondary metabolites and the coordinated action of different defence responses. Here, we review the current understanding on the composition and activity of the root microbiome and how different plant molecules can shape the structure of the root-associated microbial communities. Examples are given on interactions that occur in the rhizosphere between plants and soilborne fungi. We also present some well-established examples of microbiome harnessing to highlight how plants can maximize their fitness by selecting their microbiome. Understanding how plants manipulate their microbiome can aid in the design of next-generation microbial inoculants for targeted disease suppression and enhanced plant growth.

Architecture & Planning2020Frontiers Media
Periodicals

Acute Septic Arthritis

Acute septic arthritis may develop as a result of hematogenous seeding, direct introduction, or extension from a contiguous focus of infection. The pathogenesis of acute septic arthritis is multifactorial and depends on the interaction of the host immune response and the adherence factors, toxins, and immunoavoidance strategies of the invading pathogen. Neisseria gonorrhoeae and Staphylococcus aureus are used in discussing the host-pathogen interaction in the pathogenesis of acute septic arthritis. While diagnosis rests on isolation of the bacterial species from synovial fluid samples, patient history, clinical presentation, laboratory findings, and imaging studies are also important. Acute nongonococcal septic arthritis is a medical emergency that can lead to significant morbidity and mortality. Therefore, prompt recognition, rapid and aggressive antimicrobial therapy, and surgical treatment are critical to ensuring a good prognosis. Even with prompt diagnosis and treatment, high mortality and morbidity rates still occur. In contrast, gonococcal arthritis is often successfully treated with antimicrobial therapy alone and demonstrates a very low rate of complications and an excellent prognosis for full return of normal joint function. In the case of prosthetic joint infections, the hardware must be eventually removed by a two-stage revision in order to cure the infection.

Architecture & Planning2002American Society for Microbiology
Periodicals

Preparations, Properties, and Applications of Polyaniline and Polyaniline Thin Films—A Review

Polyaniline (PANI) is a famous conductive polymer, and it has received tremendous consideration from researchers in the field of nanotechnology for the improvement of sensors, optoelectronic devices, and photonic devices. PANI is doped easily by different acids and dopants because of its easy synthesis and remarkable environmental stability. This review focuses on different preparation processes of PANI thin film by chemical and physical methods. Several features of PANI thin films, such as their magnetic, redox, and antioxidant, anti-corrosion, and electrical and sensing properties, are discussed in this review. PANI is a highly conductive polymer. Given its unique properties, easy synthesis, low cost, and high environmental stability in various applications such as electronics, drugs, and anti-corrosion materials, it has attracted extensive attention. The most important PANI applications are briefly reviewed at the end of this review.

Architecture & Planning2021Multidisciplinary Digital Publishing Institute
Periodicals

Experience-based Co-design and Healthcare Improvement: Realizing Participatory Design in the Public Sector

Over the last decade, growing attention has been paid to the potential value of design theory and practice in improving public services. Experience-based Co-design (EBCD) is a participatory research approach that draws upon design tools and ways of thinking in order to bring healthcare staff and patients together to improve the quality of care. The co-design process that is integral to EBCD is powerful but also challenging, as it requires both staff and patients to renegotiate their roles and expectations as part of a reconfiguration of the relationships of power between citizens and public services. In this paper, we reflect upon the implementation and adaptation of EBCD in a variety of projects and on the challenges of co-design work within healthcare settings. Our discussion aims to contribute to the growing field of service design and to encourage further research into how co-design processes shape—and are shaped by—the power relations that characterize contemporary public services.

Architecture & Planning2015Routledge