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Periodicals

Multiple sclerosis

Multiple sclerosis (MS) is a multifocal demyelinating disease with progressive neurodegeneration caused by an autoimmune response to self-antigens in a genetically susceptible individual. While the formation and persistence of meningeal lymphoid follicles suggest persistence of antigens to drive the continuing inflammatory and humoral response, the identity of an antigen or infectious agent leading to the oligoclonal expansion of B and T cells is unknown. In this review we examine new paradigms for understanding the immunopathology of MS, present recent data defining the common genetic variants underlying disease susceptibility, and explore how improved understanding of immune pathway disruption can inform MS prognosis and treatment decisions.

Architecture & Planning• 2012• American Society for Clinical Investigation
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Routing Protocols in Wireless Sensor Networks - A Survey

Advances in wireless sensor network (WSN) technology has provided the availability of small and low-cost sensor nodes with capability of sensing various types of physical and environmental conditions, data processing, and wireless communication. Variety of sensing capabilities results in profusion of application areas. However, the characteristics of wireless sensor networks require more effective methods for data forwarding and processing.

Architecture & Planning• 2010
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Tumor Cell Marker PVRL4 (Nectin 4) Is an Epithelial Cell Receptor for Measles Virus

Vaccine and laboratory adapted strains of measles virus can use CD46 as a receptor to infect many human cell lines. However, wild type isolates of measles virus cannot use CD46, and they infect activated lymphocytes, dendritic cells, and macrophages via the receptor CD150/SLAM. Wild type virus can also infect epithelial cells of the respiratory tract through an unidentified receptor. We demonstrate that wild type measles virus infects primary airway epithelial cells grown in fetal calf serum and many adenocarcinoma cell lines of the lung, breast, and colon. Transfection of non-infectable adenocarcinoma cell lines with an expression vector encoding CD150/SLAM rendered them susceptible to measles virus, indicating that they were virus replication competent, but lacked a receptor for virus attachment and entry. Microarray analysis of susceptible versus non-susceptible cell lines was performed, and comparison of membrane protein gene transcripts produced a list of 11 candidate receptors. Of these, only the human tumor cell marker PVRL4 (Nectin 4) rendered cells amenable to measles virus infections. Flow cytometry confirmed that PVRL4 is highly expressed on the surfaces of susceptible lung, breast, and colon adenocarcinoma cell lines. Measles virus preferentially infected adenocarcinoma cell lines from the apical surface, although basolateral infection was observed with reduced kinetics. Confocal immune fluorescence microscopy and surface biotinylation experiments revealed that PVRL4 was expressed on both the apical and basolateral surfaces of these cell lines. Antibodies and siRNA directed against PVRL4 were able to block measles virus infections in MCF7 and NCI-H358 cancer cells. A virus binding assay indicated that PVRL4 was a bona fide receptor that supported virus attachment to the host cell. Several strains of measles virus were also shown to use PVRL4 as a receptor. Measles virus infection reduced PVRL4 surface expression in MCF7 cells, a property that is characteristic of receptor-associated viral infections.

Architecture & Planning• 2011• Public Library of Science
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The Evolution of Quantum Key Distribution Networks: On the Road to the Qinternet

Quantum key distribution (QKD) constitutes a symmetric secret key negotiation protocol capable of maintaining information-theoretic security. Given the recent advances in QKD networks, they have evolved from academic research to some preliminary applications. A QKD network consists of two or more QKD nodes interconnected by optical fiber or free space links. The secret keys are negotiated between any pair of QKD nodes, and then they can be delivered to multiple users in various areas for ensuring long-term protection and forward secrecy. We commence by introducing the QKD basics, followed by reviewing the development of QKD networks and their implementation in practice. Subsequently, we describe the general QKD network architecture, its elements, as well as its interfaces and protocols. Next, we provide an in-depth overview of the associated physical layer and network layer solutions, followed by the standardization efforts as well as the application scenarios associated with QKD networks. Finally, we discuss the potential future research directions and provide design guidelines for QKD networks.

Architecture & Planning• 2022• Institute of Electrical and Electronics Engineers
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Introduction of Microbial Biopolymers in Soil Treatment for Future Environmentally-Friendly and Sustainable Geotechnical Engineering

Soil treatment and improvement is commonly performed in the field of geotechnical engineering. Methods and materials to achieve this such as soil stabilization and mixing with cementitious binders have been utilized in engineered soil applications since the beginning of human civilization. Demand for environment-friendly and sustainable alternatives is currently rising. Since cement, the most commonly applied and effective soil treatment material, is responsible for heavy greenhouse gas emissions, alternatives such as geosynthetics, chemical polymers, geopolymers, microbial induction, and biopolymers are being actively studied. This study provides an overall review of the recent applications of biopolymers in geotechnical engineering. Biopolymers are microbially induced polymers that are high-tensile, innocuous, and eco-friendly. Soil–biopolymer interactions and related soil strengthening mechanisms are discussed in the context of recent experimental and microscopic studies. In addition, the economic feasibility of biopolymer implementation in the field is analyzed in comparison to ordinary cement, from environmental perspectives. Findings from this study demonstrate that biopolymers have strong potential to replace cement as a soil treatment material within the context of environment-friendly construction and development. Moreover, continuing research is suggested to ensure performance in terms of practical implementation, reliability, and durability of in situ biopolymer applications for geotechnical engineering purposes.

Architecture & Planning• 2016• Multidisciplinary Digital Publishing Institute
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The Fast Downward Planning System

Fast Downward is a classical planning system based on heuristic search. It can deal with general deterministic planning problems encoded in the propositional fragment of PDDL2.2, including advanced features like ADL conditions and effects and derived predicates (axioms). Like other well-known planners such as HSP and FF, Fast Downward is a progression planner, searching the space of world states of a planning task in the forward direction. However, unlike other PDDL planning systems, Fast Downward does not use the propositional PDDL representation of a planning task directly. Instead, the input is first translated into an alternative representation called multi-valued planning tasks, which makes many of the implicit constraints of a propositional planning task explicit. Exploiting this alternative representation, Fast Downward uses hierarchical decompositions of planning tasks for computing its heuristic function, called the causal graph heuristic, which is very different from traditional HSP-like heuristics based on ignoring negative interactions of operators. In this article, we give a full account of Fast Downward's approach to solving multi-valued planning tasks. We extend our earlier discussion of the causal graph heuristic to tasks involving axioms and conditional effects and present some novel techniques for search control that are used within Fast Downward's best-first search algorithm: preferred operators transfer the idea of helpful actions from local search to global best-first search, deferred evaluation of heuristic functions mitigates the negative effect of large branching factors on search performance, and multi-heuristic best-first search combines several heuristic evaluation functions within a single search algorithm in an orthogonal way. We also describe efficient data structures for fast state expansion (successor generators and axiom evaluators) and present a new non-heuristic search algorithm called focused iterative-broadening search, which utilizes the information encoded in causal graphs in a novel way. Fast Downward has proven remarkably successful: It won the "classical'' (i.e., propositional, non-optimising) track of the 4th International Planning Competition at ICAPS 2004, following in the footsteps of planners such as FF and LPG. Our experiments show that it also performs very well on the benchmarks of the earlier planning competitions and provide some insights about the usefulness of the new search enhancements.

Architecture & Planning• 2006• AI Access Foundation
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Mapping the Economic Costs and Benefits of Conservation

Resources for biodiversity conservation are severely limited, requiring strategic investment. Understanding both the economic benefits and costs of conserving ecosystems will help to allocate scarce dollars most efficiently. However, although cost-benefit analyses are common in many areas of policy, they are not typically used in conservation planning. We conducted a spatial evaluation of the costs and benefits of conservation for a landscape in the Atlantic forests of Paraguay. We considered five ecosystem services (i.e., sustainable bushmeat harvest, sustainable timber harvest, bioprospecting for pharmaceutical products, existence value, and carbon storage in aboveground biomass) and compared them to estimates of the opportunity costs of conservation. We found a high degree of spatial variability in both costs and benefits over this relatively small (approximately 3,000 km(2)) landscape. Benefits exceeded costs in some areas, with carbon storage dominating the ecosystem service values and swamping opportunity costs. Other benefits associated with conservation were more modest and exceeded costs only in protected areas and indigenous reserves. We used this cost-benefit information to show that one potential corridor between two large forest patches had net benefits that were three times greater than two otherwise similar alternatives. Spatial cost-benefit analysis can powerfully inform conservation planning, even though the availability of relevant data may be limited, as was the case in our study area. It can help us understand the synergies between biodiversity conservation and economic development when the two are indeed aligned and to clearly understand the trade-offs when they are not.

Architecture & Planning• 2006• Public Library of Science
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Meaningful Human Control over Autonomous Systems: A Philosophical Account

Debates on lethal autonomous weapon systems have proliferated in the past 5 years. Ethical concerns have been voiced about a possible raise in the number of wrongs and crimes in military operations and about the creation of a "responsibility gap" for harms caused by these systems. To address these concerns, the principle of "meaningful human control" has been introduced in the legal-political debate; according to this principle, humans not computers and their algorithms should ultimately remain in control of, and thus morally responsible for, relevant decisions about (lethal) military operations. However, policy-makers and technical designers lack a detailed theory of what "meaningful human control" exactly means. In this paper, we lay the foundation of a philosophical account of meaningful human control, based on the concept of "guidance control" as elaborated in the philosophical debate on free will and moral responsibility. Following the ideals of "Responsible Innovation" and "Value-sensitive Design," our account of meaningful human control is cast in the form of design requirements. We identify two general necessary conditions to be satisfied for an autonomous system to remain under meaningful human control: first, a "tracking" condition, according to which the system should be able to respond to both the relevant moral reasons of the humans designing and deploying the system and the relevant facts in the environment in which the system operates; second, a "tracing" condition, according to which the system should be designed in such a way as to grant the possibility to always trace back the outcome of its operations to at least one human along the chain of design and operation. As we think that meaningful human control can be one of the central notions in ethics of robotics and AI, in the last part of the paper, we start exploring the implications of our account for the design and use of non-military autonomous systems, for instance, self-driving cars.

Architecture & Planning• 2018• Frontiers Media
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Periodicals

On Predictive Maintenance in Industry 4.0: Overview, Models, and Challenges

In the era of the fourth industrial revolution, several concepts have arisen in parallel with this new revolution, such as predictive maintenance, which today plays a key role in sustainable manufacturing and production systems by introducing a digital version of machine maintenance. The data extracted from production processes have increased exponentially due to the proliferation of sensing technologies. Even if Maintenance 4.0 faces organizational, financial, or even data source and machine repair challenges, it remains a strong point for the companies that use it. Indeed, it allows for minimizing machine downtime and associated costs, maximizing the life cycle of the machine, and improving the quality and cadence of production. This approach is generally characterized by a very precise workflow, starting with project understanding and data collection and ending with the decision-making phase. This paper presents an exhaustive literature review of methods and applied tools for intelligent predictive maintenance models in Industry 4.0 by identifying and categorizing the life cycle of maintenance projects and the challenges encountered, and presents the models associated with this type of maintenance: condition-based maintenance (CBM), prognostics and health management (PHM), and remaining useful life (RUL). Finally, a novel applied industrial workflow of predictive maintenance is presented including the decision support phase wherein a recommendation for a predictive maintenance platform is presented. This platform ensures the management and fluid data communication between equipment throughout their life cycle in the context of smart maintenance.

Architecture & Planning• 2022• Multidisciplinary Digital Publishing Institute
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Spectra stable blue perovskite light-emitting diodes

Device performance and in particular device stability for blue perovskite light-emitting diodes (PeLEDs) remain considerable challenges for the whole community. In this manuscript, we conceive an approach by tuning the 'A-site' cation composition of perovskites to develop blue-emitters. We herein report a Rubidium-Cesium alloyed, quasi-two-dimensional perovskite and demonstrate its great potential for pure-blue PeLED applications. Composition engineering and in-situ passivation are conducted to further improve the material's emission property and stabilities. Consequently, we get a prominent film photoluminescence quantum yield of around 82% under low excitation density. Encouraged by these findings, we finally achieve a spectra-stable blue PeLED with the peak external quantum efficiency of 1.35% and a half-lifetime of 14.5 min, representing the most efficient and stable pure-blue PeLEDs reported so far. The strategy is also demonstrated to be able to generate efficient perovskite blue emitters and PeLEDs in the whole blue spectral region (from 454 to 492 nm).

Architecture & Planning• 2019• Nature Portfolio
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Next-generation applications for integrated perovskite solar cells

Abstract Organic/inorganic metal halide perovskites attract substantial attention as key materials for next-generation photovoltaic technologies due to their potential for low cost, high performance, and solution processability. The unique properties of perovskites and the rapid advances that have been made in solar cell performance have facilitated their integration into a broad range of practical applications, including tandem solar cells, building-integrated photovoltaics, space applications, integration with batteries and supercapacitors for energy storage systems, and photovoltaic-driven catalysis. In this Review, we outline notable achievements that have been made in these photovoltaic-integrated technologies. Outstanding challenges and future perspectives for the development of these fields and potential next-generation applications are discussed.

Architecture & Planning• 2023• Nature Portfolio
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A Comprehensive Survey on Millimeter Wave Communications for Fifth-Generation Wireless Networks: Feasibility and Challenges

Fifth-generation (5G) cellular networks will almost certainly operate in the high-bandwidth, underutilized millimeter-wave (mmWave) frequency spectrum, which offers the potentiality of high-capacity wireless transmission of multi-gigabit-per-second (Gbps) data rates. Despite the enormous available bandwidth potential, mmWave signal transmissions suffer from fundamental technical challenges like severe path loss, sensitivity to blockage, directivity, and narrow beamwidth, due to its short wavelengths. To effectively support system design and deployment, accurate channel modeling comprising several 5G technologies and scenarios is essential. This survey provides a comprehensive overview of several emerging technologies for 5G systems, such as massive multiple-input multiple-output (MIMO) technologies, multiple access technologies, hybrid analog-digital precoding and combining, non-orthogonal multiple access (NOMA), cell-free massive MIMO, and simultaneous wireless information and power transfer (SWIPT) technologies. These technologies induce distinct propagation characteristics and establish specific requirements on 5G channel modeling. To tackle these challenges, we first provide a survey of existing solutions and standards and discuss the radio-frequency (RF) spectrum and regulatory issues for mmWave communications. Second, we compared existing wireless communication techniques like sub-6-GHz WiFi and sub-6 GHz 4G LTE over mmWave communications which come with benefits comprising narrow beam, high signal quality, large capacity data transmission, and strong detection potential. Third, we describe the fundamental propagation characteristics of the mmWave band and survey the existing channel models for mmWave communications. Fourth, we track evolution and advancements in hybrid beamforming for massive MIMO systems in terms of system models of hybrid precoding architectures, hybrid analog and digital precoding/combining matrices, with the potential antenna configuration scenarios and mmWave channel estimation (CE) techniques. Fifth, we extend the scope of the discussion by including multiple access technologies for mmWave systems such as non-orthogonal multiple access (NOMA) and space-division multiple access (SDMA), with limited RF chains at the base station. Lastly, we explore the integration of SWIPT in mmWave massive MIMO systems, with limited RF chains, to realize spectrally and energy-efficient communications.

Architecture & Planning• 2020• Institute of Electrical and Electronics Engineers
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UniMiB SHAR: A Dataset for Human Activity Recognition Using Acceleration Data from Smartphones

Smartphones, smartwatches, fitness trackers, and ad-hoc wearable devices are being increasingly used to monitor human activities. Data acquired by the hosted sensors are usually processed by machine-learning-based algorithms to classify human activities. The success of those algorithms mostly depends on the availability of training (labeled) data that, if made publicly available, would allow researchers to make objective comparisons between techniques. Nowadays, there are only a few publicly available data sets, which often contain samples from subjects with too similar characteristics, and very often lack specific information so that is not possible to select subsets of samples according to specific criteria. In this article, we present a new dataset of acceleration samples acquired with an Android smartphone designed for human activity recognition and fall detection. The dataset includes 11,771 samples of both human activities and falls performed by 30 subjects of ages ranging from 18 to 60 years. Samples are divided in 17 fine grained classes grouped in two coarse grained classes: one containing samples of 9 types of activities of daily living (ADL) and the other containing samples of 8 types of falls. The dataset has been stored to include all the information useful to select samples according to different criteria, such as the type of ADL performed, the age, the gender, and so on. Finally, the dataset has been benchmarked with four different classifiers and with two different feature vectors. We evaluated four different classification tasks: fall vs. no fall, 9 activities, 8 falls, 17 activities and falls. For each classification task, we performed a 5-fold cross-validation (i.e., including samples from all the subjects in both the training and the test dataset) and a leave-one-subject-out cross-validation (i.e., the test data include the samples of a subject only, and the training data, the samples of all the other subjects). Regarding the classification tasks, the major findings can be summarized as follows: (i) it is quite easy to distinguish between falls and ADLs, regardless of the classifier and the feature vector selected. Indeed, these classes of activities present quite different acceleration shapes that simplify the recognition task; (ii) on average, it is more difficult to distinguish between types of falls than between types of activities, regardless of the classifier and the feature vector selected. This is due to the similarity between the acceleration shapes of different kinds of falls. On the contrary, ADLs acceleration shapes present differences except for a small group. Finally, the evaluation shows that the presence of samples of the same subject both in the training and in the test datasets, increases the performance of the classifiers regardless of the feature vector used. This happens because each human subject differs from other subjects in performing activities even if she shares with them the same physical characteristics.

Architecture & Planning• 2017• Multidisciplinary Digital Publishing Institute
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A Drought Resistance-Promoting Microbiome Is Selected by Root System under Desert Farming

BACKGROUND: Traditional agro-systems in arid areas are a bulwark for preserving soil stability and fertility, in the sight of "reverse desertification". Nevertheless, the impact of desert farming practices on the diversity and abundance of the plant associated microbiome is poorly characterized, including its functional role in supporting plant development under drought stress. METHODOLOGY/PRINCIPAL FINDINGS: We assessed the structure of the microbiome associated to the drought-sensitive pepper plant (Capsicum annuum L.) cultivated in a traditional Egyptian farm, focusing on microbe contribution to a crucial ecosystem service, i.e. plant growth under water deficit. The root system was dissected by sampling root/soil with a different degree of association to the plant: the endosphere, the rhizosphere and the root surrounding soil that were compared to the uncultivated soil. Bacterial community structure and diversity, determined by using Denaturing Gradient Gel Electrophoresis, differed according to the microhabitat, indicating a selective pressure determined by the plant activity. Similarly, culturable bacteria genera showed different distribution in the three root system fractions. Bacillus spp. (68% of the isolates) were mainly recovered from the endosphere, while rhizosphere and the root surrounding soil fractions were dominated by Klebsiella spp. (61% and 44% respectively). Most of the isolates (95%) presented in vitro multiple plant growth promoting (PGP) activities and stress resistance capabilities, but their distribution was different among the root system fractions analyzed, with enhanced abilities for Bacillus and the rhizobacteria strains. We show that the C. annuum rhizosphere under desert farming enriched populations of PGP bacteria capable of enhancing plant photosynthetic activity and biomass synthesis (up to 40%) under drought stress. CONCLUSIONS/SIGNIFICANCE: Crop cultivation provides critical ecosystem services in arid lands with the plant root system acting as a "resource island" able to attract and select microbial communities endowed with multiple PGP traits that sustain plant development under water limiting conditions.

Architecture & Planning• 2012• Public Library of Science
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Distinct neural signatures detected for ADHD subtypes after controlling for micro-movements in resting state functional connectivity MRI data

In recent years, there has been growing enthusiasm that functional magnetic resonance imaging (MRI) could achieve clinical utility for a broad range of neuropsychiatric disorders. However, several barriers remain. For example, the acquisition of large-scale datasets capable of clarifying the marked heterogeneity that exists in psychiatric illnesses will need to be realized. In addition, there continues to be a need for the development of image processing and analysis methods capable of separating signal from artifact. As a prototypical hyperkinetic disorder, and movement-related artifact being a significant confound in functional imaging studies, ADHD offers a unique challenge. As part of the ADHD-200 Global Competition and this special edition of Frontiers, the ADHD-200 Consortium demonstrates the utility of an aggregate dataset pooled across five institutions in addressing these challenges. The work aimed to (1) examine the impact of emerging techniques for controlling for "micro-movements," and (2) provide novel insights into the neural correlates of ADHD subtypes. Using support vector machine (SVM)-based multivariate pattern analysis (MVPA) we show that functional connectivity patterns in individuals are capable of differentiating the two most prominent ADHD subtypes. The application of graph-theory revealed that the Combined (ADHD-C) and Inattentive (ADHD-I) subtypes demonstrated some overlapping (particularly sensorimotor systems), but unique patterns of atypical connectivity. For ADHD-C, atypical connectivity was prominent in midline default network components, as well as insular cortex; in contrast, the ADHD-I group exhibited atypical patterns within the dlPFC regions and cerebellum. Systematic motion-related artifact was noted, and highlighted the need for stringent motion correction. Findings reported were robust to the specific motion correction strategy employed. These data suggest that resting-state functional connectivity MRI (rs-fcMRI) data can be used to characterize individual patients with ADHD and to identify neural distinctions underlying the clinical heterogeneity of ADHD.

Architecture & Planning• 2013• Frontiers Media
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The spatial coding model of visual word identification.

Visual word identification requires readers to code the identity and order of the letters in a word and match this code against previously learned codes. Current models of this lexical matching process posit context-specific letter codes in which letter representations are tied to either specific serial positions or specific local contexts (e.g., letter clusters). The spatial coding model described here adopts a different approach to letter position coding and lexical matching based on context-independent letter representations. In this model, letter position is coded dynamically, with a scheme called spatial coding. Lexical matching is achieved via a method called superposition matching, in which input codes and learned codes are matched on the basis of the relative positions of their common letters. Simulations of the model illustrate its ability to explain a broad range of results from the masked form priming literature, as well as to capture benchmark findings from the unprimed lexical decision task.

Architecture & Planning• 2010• American Psychological Association
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What Is eHealth (4): A Scoping Exercise to Map the Field

BACKGROUND: Lack of consensus on the meaning of eHealth has led to uncertainty among academics, policymakers, providers and consumers. This project was commissioned in light of the rising profile of eHealth on the international policy agenda and the emerging UK National Programme for Information Technology (now called Connecting for Health) and related developments in the UK National Health Service. OBJECTIVES: To map the emergence and scope of eHealth as a topic and to identify its place within the wider health informatics field, as part of a larger review of research and expert analysis pertaining to current evidence, best practice and future trends. METHODS: Multiple databases of scientific abstracts were explored in a nonsystematic fashion to assess the presence of eHealth or conceptually related terms within their taxonomies, to identify journals in which articles explicitly referring to eHealth are contained and the topics covered, and to identify published definitions of the concept. The databases were Medline (PubMed), the Cumulative Index of Nursing and Allied Health Literature (CINAHL), the Science Citation Index (SCI), the Social Science Citation Index (SSCI), the Cochrane Database (including Dare, Central, NHS Economic Evaluation Database [NHS EED], Health Technology Assessment [HTA] database, NHS EED bibliographic) and ISTP (now known as ISI proceedings). We used the search query, "Ehealth OR e-health OR e*health". The timeframe searched was 1997-2003, although some analyses contain data emerging subsequent to this period. This was supplemented by iterative searches of Web-based sources, such as commercial and policy reports, research commissioning programmes and electronic news pages. Definitions extracted from both searches were thematically analyzed and compared in order to assess conceptual heterogeneity. RESULTS: The term eHealth only came into use in the year 2000, but has since become widely prevalent. The scope of the topic was not immediately discernable from that of the wider health informatics field, for which over 320000 publications are listed in Medline alone, and it is not explicitly represented within the existing Medical Subject Headings (MeSH) taxonomy. Applying eHealth as narrative search term to multiple databases yielded 387 relevant articles, distributed across 154 different journals, most commonly related to information technology and telemedicine, but extending to such areas as law. Most eHealth articles are represented on Medline. Definitions of eHealth vary with respect to the functions, stakeholders, contexts and theoretical issues targeted. Most encompass a broad range of medical informatics applications either specified (eg, decision support, consumer health information) or presented in more general terms (eg, to manage, arrange or deliver health care). However the majority emphasize the communicative functions of eHealth and specify the use of networked digital technologies, primarily the Internet, thus differentiating eHealth from the field of medical informatics. While some definitions explicitly target health professionals or patients, most encompass applications for all stakeholder groups. The nature of the scientific and broader literature pertaining to eHealth closely reflects these conceptualizations. CONCLUSIONS: We surmise that the field -- as it stands today -- may be characterized by the global definitions suggested by Eysenbach and Eng.

Architecture & Planning• 2005• JMIR Publications
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Challenges Toward Wireless Communications for High-Speed Railway

High-speed railway (HSR) brings convenience to peoples' lives and is generally considered as one of the most sustainable developments for ground transportation. One of the important parts of HSR construction is the signaling system, which is also called the “operation control system,” where wireless communications play a key role in the transmission of train control data. We discuss in detail the main differences in scientific research for wireless communications between the HSR operation scenarios and the conventional public land mobile scenarios. The latest research progress in wireless channel modeling in viaducts, cuttings, and tunnels scenarios are discussed. The characteristics of nonstationary channel and the line-of-sight (LOS) sparse and LOS multiple-input-multiple-output channels, which are the typical channels in HSR scenarios, are analyzed. Some novel concepts such as composite transportation and key challenging techniques such as train-to-train communication, vacuum maglev train techniques, the security for HSR, and the fifth-generation wireless communications related techniques for future HSR development for safer, more comfortable, and more secure HSR operation are also discussed.

Architecture & Planning• 2014• Institute of Electrical and Electronics Engineers
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Soil and Crop Management Strategies to Ensure Higher Crop Productivity within Sustainable Environments

The rising population and reduction in the amount of land and some other resources have created tremendous pressure on current agricultural producers to meet the increasing food demands. To cope with this challenge, certain key inputs, such as fertilizers and other chemicals, are overused, which are worsening the surroundings. This intensive agricultural production without adherence to ecological sustainability has led to declining soil health, land degradation, and severe environmental problems. So, future efforts to feed the growing population should aim for greater agricultural production within sustainable environments. In this regard, innovative steps are needed, as business-as-usual policies lack the potential to cope with these challenges. The concept of agricultural sustainability and various soil and crop management strategies (SCMS) that have been designed to optimize crop yield under sustainable environmental conditions are discussed, including nutrient management, site specific nutrient management (SSNM), integrated nutrient management (INM), integrated soil fertility management (ISFM), integrated soil-crop system management (ISSM), ridge-furrow mulching systems (RFMS), sustainable water management (SWM), conservation agriculture (CA), sustainable land management (SLM), vertical/sky farming, and integrated crop management, and breeding strategies as well as other approaches combined with technological and behavioural changes. The present review suggests that a sustainable production system can be developed by combining the multifaceted efforts under SCMS practices with short- and long-term preventive measures. Reducing chemicals’ usage, such as that of fertilizers and pesticides, plus improvements in the crop input use efficiency could minimize greenhouse gases emissions while protecting the environment. Sustainable agriculture holds promise for humankind and the planet Earth, and it can be successful if all developed and developing nations stand together to seek ‘our common future’ to produce more food while generating less environmental pressure.

Architecture & Planning• 2019• Multidisciplinary Digital Publishing Institute
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Food Traceability on Blockchain: Walmart’s Pork and Mango Pilots with IBM

In response to food contamination scandals worldwide, retail giant Walmart is tackling food safety in the supply chain using blockchain technology. In 2016, it established the Walmart Food Safety Collaboration Center in Beijing and plans to invest $25 million over five years to research global food safety (Yiannas and Liu, 2017). Using IBM’s blockchain solution based on Hyperledger Fabric, Walmart has successfully completed two blockchain pilots: pork in China and mangoes in the Americas (IBM, 2017). With a farm-to-table approach, Walmart’s blockchain solution reduced time for tracking mango origins from seven days to 2.2 seconds and promoted greater transparency across Walmart’s food supply chain (Yiannas, 2017). IBM called it “complete end-to-end traceability” (McDermott, 2017). The case highlights the challenges of implementing blockchain technology in the food supply chain and the opportunities for deploying blockchain solutions throughout the global food ecosystem to increase safety and reduce waste.

Architecture & Planning• 2018
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The Hyper Suprime-Cam software pipeline

Abstract In this paper, we describe the optical imaging data processing pipeline developed for the Subaru Telescope’s Hyper Suprime-Cam (HSC) instrument. The HSC Pipeline builds on the prototype pipeline being developed by the Large Synoptic Survey Telescope’s Data Management system, adding customizations for HSC, large-scale processing capabilities, and novel algorithms that have since been reincorporated into the LSST codebase. While designed primarily to reduce HSC Subaru Strategic Program (SSP) data, it is also the recommended pipeline for reducing general-observer HSC data. The HSC pipeline includes high-level processing steps that generate coadded images and science-ready catalogs as well as low-level detrending and image characterizations.

Architecture & Planning• 2017• Oxford University Press
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Periodontal Inflammation and Systemic Diseases: An Overview

Periodontitis is a common inflammatory disease of infectious origins that often evolves into a chronic condition. Aside from its importance as a stomatologic ailment, chronic periodontitis has gained relevance since it has been shown that it can develop into a systemic condition characterized by unresolved hyper-inflammation, disruption of the innate and adaptive immune system, dysbiosis of the oral, gut and other location's microbiota and other system-wide alterations that may cause, coexist or aggravate other health issues associated to elevated morbi-mortality. The relationships between the infectious, immune, inflammatory, and systemic features of periodontitis and its many related diseases are far from being fully understood and are indeed still debated. However, to date, a large body of evidence on the different biological, clinical, and policy-enabling sources of information, is available. The aim of the present work is to summarize many of these sources of information and contextualize them under a systemic inflammation framework that may set the basis to an integral vision, useful for basic, clinical, and therapeutic goals.

Architecture & Planning• 2021• Frontiers Media
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