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Periodicals

Review of Portable and Low-Cost Sensors for the Ambient Air Monitoring of Benzene and Other Volatile Organic Compounds

This article presents a literature review of sensors for the monitoring of benzene in ambient air and other volatile organic compounds. Combined with information provided by stakeholders, manufacturers and literature, the review considers commercially available sensors, including PID-based sensors, semiconductor (resistive gas sensors) and portable on-line measuring devices as for example sensor arrays. The bibliographic collection includes the following topics: sensor description, field of application at fixed sites, indoor and ambient air monitoring, range of concentration levels and limit of detection in air, model descriptions of the phenomena involved in the sensor detection process, gaseous interference selectivity of sensors in complex VOC matrix, validation data in lab experiments and under field conditions.

Architecture & Planning2017Multidisciplinary Digital Publishing Institute
Periodicals

Development of Picture Storybooks with TheoAnthropoEco Centric Approach for Elementary School Students

Learning media has a significant role in an effort to help abstract concepts so that students more easily understand these concepts. However, many teachers have difficulty in developing learning media. This study aims to develop learning media in the form of picture storybooks with a TheoAnthropoEco-centric approach that is feasible and practical for use by elementary school students. This study uses a research and development type that refers to the development stage of Borg Gall. The data was obtained using a product feasibility validation questionnaire and a teacher and student response questionnaire. The subjects of this research are media experts, material experts, linguists, class teachers and fourth-grade students of madrasah ibtidaiyah. The determination of research subjects is done by purposive sampling technique. Descriptive statistical techniques analyzed the data obtained in this study. The results showed that the picture book with the TheoAnthropoEco-centric approach developed in this study was feasible and practical for use by elementary school students. This is evidenced by the feasibility test results, which show the developed media is in the "Very Good" category. On the other hand, the results of the practicality test also show that the product developed in this study is in the "Very Good" category. Therefore, picture story books with a TheoAnthropoEco-centric approach can be used as a medium of learning at the elementary school level.

Architecture & Planning2023
Periodicals

Strategies for Preparing Albumin-based Nanoparticles for Multifunctional Bioimaging and Drug Delivery

Biosafety is the primary concern in clinical translation of nanomedicine. As an intrinsic ingredient of human blood without immunogenicity and encouraged by its successful clinical application in Abraxane, albumin has been regarded as a promising material to produce nanoparticles for bioimaging and drug delivery. The strategies for synthesizing albumin-based nanoparticles could be generally categorized into five classes: template, nanocarrier, scaffold, stabilizer and albumin-polymer conjugate. This review introduces approaches utilizing albumin in the preparation of nanoparticles and thereby provides scientists with knowledge of goal-driven design on albumin-based nanomedicine.

Architecture & Planning2017Ivyspring International Publisher
Periodicals

The Effect of Blockchain Technology on Supply Chain Sustainability Performances

Improving supply chain sustainability is an essential part of achieving the UN’s sustainable goals. Digitalization, such as blockchain technology, shows the potential to reshape supply chain management. Using distributed ledger technology, the blockchain platform provides a digital system and database to record the transactions along the supply chain. This decentralized database of transactions brings transparency, reliability, traceability, and efficiency to the supply chain management. This paper focuses on such novel blockchain-based supply chain management and its sustainability performances in the areas of environmental protection, social equity, and governance efficiency. Using a systematic literature review and two case studies, we evaluate whether the three sustainability indicators can be improved indirectly along supply chains based on blockchain technology. Our study shows that blockchain technology has the potential to improve supply chain sustainability performance, and we expect blockchain technology to rise in popularity in supply chain management.

Architecture & Planning2021Multidisciplinary Digital Publishing Institute
Periodicals

Building the Field of Health Policy and Systems Research: Framing the Questions

Following the First Global Symposium
\non Health Systems Research in
\nMontreux in November 2010, PLoS
\nMedicine commissioned three articles
\non the state-of-the-art in Health
\nPolicy and Systems Research (HPSR).
\nThree Policy Forum articles, authored
\nby a diverse group of global
\nhealth academics, critically examine
\nthe current challenges to the field
\nand lay out what is needed to build
\ncapacity in HPSR and support local
\npolicy development and health systems
\nstrengthening, especially in
\nlow- and middle-income countries.

Architecture & Planning2011Public Library of Science
Periodicals

Stochastic Geometry and Wireless Networks: Volume II Applications

This volume bears on wireless network modeling and performance analysis. The aim is to show how stochastic geometry can be used in a more or less systematic way to analyze the phenomena that arise in this context. It first focuses on medium access control mechanisms used in ad hoc networks and in cellular networks. It then discusses the use of stochastic geometry for the quantitative analysis of routing algorithms in mobile ad hoc networks. The appendix also contains a concise summary of wireless communication principles and of the network architectures considered in the two volumes.

Architecture & Planning2010Now Publishers
Periodicals

IoT and Cloud Computing Issues, Challenges and Opportunities: A Review

With the exponential growth of the Industrial Internet of Things (IIoT), multiple outlets are constantly producing a vast volume of data. It is unwise to locally store all the raw data in the IIoT devices since the energy and storage spaces of the end devices are strictly constrained. self-organization and short-range Internet of Things (IoT) networking also support outsourced data and cloud computing, independent of the distinctive resource constraint properties. For the remainder of the findings, there is a sequence of unfamiliar safeguards for IoT and cloud integration problems. The delivery of cloud computing is highly efficient, storage is becoming more and more current, and some groups are now altering their data from in house records Cloud Computing Vendors' hubs. Intensive IoT applications for workloads and data are subject to challenges while utilizing cloud computing tools. In this report, we research IoT and cloud computing and address cloud-compatible problems and computing techniques to promote the stable transition of IoT programs to the cloud.

Architecture & Planning2021
Periodicals

City Digital Twin Potentials: A Review and Research Agenda

The city digital twin is anticipated to accurately reflect and affect the city’s functions and processes to enhance its realization, operability, and management. Although research on the city digital twin is still in its infancy, the advancement of the digital twin technology is growing fast and providing viable contributions to augmenting smart city developments. This study reviews the literature to identify the current and prospective potentials and challenges of digital twin cities. A research agenda is also proposed to guide future research on the city digital twincity digital twin to reach the utmost level of a comprehensive and complete city digital twin. Enhancing the efficiency of data processing, promoting the inclusion of socio-economic components of the city, and developing mutual integration between the two counterparts of the digital twin are proposed to be the future research directions to achieve and utilize a completely mirrored city digital twin.

Architecture & Planning2021Multidisciplinary Digital Publishing Institute
Periodicals

Berberine in Cardiovascular and Metabolic Diseases: From Mechanisms to Therapeutics

Cardiovascular and metabolic diseases (CVMD) are the leading causes of death worldwide, underscoring the urgent necessity to develop new pharmacotherapies. Berberine (BBR) is an eminent component of traditional Chinese and Ayurvedic medicine for more than 2000 years. Recently, BBR has attracted much interest for its pharmacological actions in treating and/or managing CVMD. Recent discoveries of basic, translational and clinical studies have identified many novel molecular targets of BBR (such as AMPK, SIRT1, LDLR, PCSK9, and PTP1B) and provided novel evidences supporting the promising therapeutic potential of BBR to combat CVMD. Thus, this review provides a timely overview of the pharmacological properties and therapeutic application of BBR in CVMD, and underlines recent pharmacological advances which validate BBR as a promising lead drug against CVMD.

Architecture & Planning2019Ivyspring International Publisher
Periodicals

MEMS Mirrors for LiDAR: A Review

In recent years, Light Detection and Ranging (LiDAR) has been drawing extensive attention both in academia and industry because of the increasing demand for autonomous vehicles. LiDAR is believed to be the crucial sensor for autonomous driving and flying, as it can provide high-density point clouds with accurate three-dimensional information. This review presents an extensive overview of Microelectronechanical Systems (MEMS) scanning mirrors specifically for applications in LiDAR systems. MEMS mirror-based laser scanners have unrivalled advantages in terms of size, speed and cost over other types of laser scanners, making them ideal for LiDAR in a wide range of applications. A figure of merit (FoM) is defined for MEMS mirrors in LiDAR scanners in terms of aperture size, field of view (FoV) and resonant frequency. Various MEMS mirrors based on different actuation mechanisms are compared using the FoM. Finally, a preliminary assessment of off-the-shelf MEMS scanned LiDAR systems is given.

Architecture & Planning2020Multidisciplinary Digital Publishing Institute
Periodicals

Not all minds that wander are lost: the importance of a balanced perspective on the mind-wandering state

The waking mind is often occupied with mental contents that are minimally constrained by events in the here and now. These self-generated thoughts-e.g., mind-wandering or daydreaming-interfere with external task performance and can be a marker for unhappiness and even psychiatric problems. They also occupy our thoughts for upwards of half of the time, and under non-demanding conditions they (i) allow us to connect our past and future selves together, (ii) help us make successful long-term plans and (iii) can provide a source of creative inspiration. The lengths that the mind goes to self-generate thought, coupled with its apparent functionality, suggest that the mind places a higher priority on such cognition than on many other mental acts. Although mind-wandering may be unpleasant for the individual who experiences it and disruptive to the tasks of the moment, self-generated thought allows consciousness freedom from the here and now and so reflects a key evolutionary adaptation for the mind. Here we synthesize recent literature from cognitive and clinical psychology and propose two formal hypotheses that (1) highlight task context and thought content as critical factors that constrain the costs and benefits of self-generated thought and (2) provide direction on ways to investigate the costs and benefits from an impartial perspective.

Architecture & Planning2013Frontiers Media
Periodicals

Environmental Impacts of the Deep-Water Oil and Gas Industry: A Review to Guide Management Strategies

The industrialization of the deep sea is expanding worldwide. Increasing oil and gas exploration activities in the absence of sufficient baseline data in deep-sea ecosystems has made environmental management challenging. Here, we review the types of activities that are associated with global offshore oil and gas development in water depths over 200 m, the typical impacts of these activities, some of the more extreme impacts of accidental oil and gas releases, and the current state of management in the major regions of offshore industrial activity including 18 exclusive economic zones. Direct impacts of infrastructure installation, including sediment resuspension and burial by seafloor anchors and pipelines, are typically restricted to a radius of ~100 m on from the installation on the seafloor. Discharges of water-based and low-toxicity oil-based drilling muds and produced water can extend over 2 km, while the ecological impacts at the population and community levels on the seafloor are most commonly on the order of 200–300 m from their source. These impacts may persist in the deep sea for many years and likely longer for its more fragile ecosystems, such as cold-water corals. This synthesis of information provides the basis for a series of recommendations for the management of offshore oil and gas development. An effective management strategy, aimed at minimizing risk of significant environmental harm, will typically encompass regulations of the activity itself (e.g., discharge practices, materials used), combined with spatial (e.g., avoidance rules and marine protected areas), and temporal measures (e.g., restricted activities during peak reproductive periods). Spatial management measures that encompass representatives of all of the regional deep-sea community types is important in this context. Implementation of these management strategies should consider minimum buffer zones to displace industrial activity beyond the range of typical impacts: at least 2 km from any discharge points and surface infrastructure and 200 m from seafloor infrastructure with no expected discharges. Although managing natural resources is, arguably, more challenging in deep-water environments, inclusion of these proven conservation tools contributes to robust environmental management strategies for oil and gas extraction in the deep sea.

Architecture & Planning2016Frontiers Media
Periodicals

Smartphone Sensors for Health Monitoring and Diagnosis

Over the past few decades, we have witnessed a dramatic rise in life expectancy owing to significant advances in medical science and technology, medicine as well as increased awareness about nutrition, education, and environmental and personal hygiene. Consequently, the elderly population in many countries are expected to rise rapidly in the coming years. A rapidly rising elderly demographics is expected to adversely affect the socioeconomic systems of many nations in terms of costs associated with their healthcare and wellbeing. In addition, diseases related to the cardiovascular system, eye, respiratory system, skin and mental health are widespread globally. However, most of these diseases can be avoided and/or properly managed through continuous monitoring. In order to enable continuous health monitoring as well as to serve growing healthcare needs; affordable, non-invasive and easy-to-use healthcare solutions are critical. The ever-increasing penetration of smartphones, coupled with embedded sensors and modern communication technologies, make it an attractive technology for enabling continuous and remote monitoring of an individual's health and wellbeing with negligible additional costs. In this paper, we present a comprehensive review of the state-of-the-art research and developments in smartphone-sensor based healthcare technologies. A discussion on regulatory policies for medical devices and their implications in smartphone-based healthcare systems is presented. Finally, some future research perspectives and concerns regarding smartphone-based healthcare systems are described.

Architecture & Planning2019Multidisciplinary Digital Publishing Institute
Periodicals

A Review of ChatGPT AI's Impact on Several Business Sectors

Almost every few decades, there is an innovation that completely changes the world. We mean innovations that play a vital role in raising the standard of living, such as the internet or airplanes. What will be the next definitive moment in history. It's here, and it's called Chat GPT. It was created by the artificial intelligence research firm Open AI. ChatGPT is a natural language processing (NLP) model that combines GPT-2, a transformer-based language model developed by OpenAI, with supervised and reinforcement learning techniques to fine-tune it (an approach to transfer learning) on the GPT-3 group of large language patterns developed by OpenAI. The model enables users to interact naturally with an AI system through text-based conversations. It could be used for customer service applications and to create virtual assistants for voice and text conversations. ChatGPT also provides features such as topic detection, emotion detection, and sentiment analysis capabilities to help users understand their conversation partner better. Additionally, it has the capability to generate multiple conversation threads in order to create more realistic interactions between user and bot. We will also explore some of the challenges facing AI development and how we can overcome them. This article is about the recent developments in the field of artificial intelligence (AI). AI has advanced significantly over recent years, with a wide range of applications and new technologies being developed. And discuss a few of these advancements and use to improve human lives. In this paper, we discuss how ChatGPT - a Natural Language Generation (NLG) model powered by OpenAI's GPT-3 technology - can enhance e-commerce via chat, as well as other sectors such as education, entertainment, finance, health, news and productivity. We will analyze the current use-cases of ChatGPT in these sectors and explore possible future applications. We will also discuss how this technology can use to create more personalized content for users. Finally, we will look at how ChatGPT can help to make customer service more efficient and effective for businesses.

Architecture & Planning2023European Organization for Nuclear Research
Periodicals

Strigolactone Can Promote or Inhibit Shoot Branching by Triggering Rapid Depletion of the Auxin Efflux Protein PIN1 from the Plasma Membrane

Plants continuously extend their root and shoot systems through the action of meristems at their growing tips. By regulating which meristems are active, plants adjust their body plans to suit local environmental conditions. The transport network of the phytohormone auxin has been proposed to mediate this systemic growth coordination, due to its self-organising, environmentally sensitive properties. In particular, a positive feedback mechanism termed auxin transport canalization, which establishes auxin flow from active shoot meristems (auxin sources) to the roots (auxin sinks), has been proposed to mediate competition between shoot meristems and to balance shoot and root growth. Here we provide strong support for this hypothesis by demonstrating that a second hormone, strigolactone, regulates growth redistribution in the shoot by rapidly modulating auxin transport. A computational model in which strigolactone action is represented as an increase in the rate of removal of the auxin export protein, PIN1, from the plasma membrane can reproduce both the auxin transport and shoot branching phenotypes observed in various mutant combinations and strigolactone treatments, including the counterintuitive ability of strigolactones either to promote or inhibit shoot branching, depending on the auxin transport status of the plant. Consistent with this predicted mode of action, strigolactone signalling was found to trigger PIN1 depletion from the plasma membrane of xylem parenchyma cells in the stem. This effect could be detected within 10 minutes of strigolactone treatment and was independent of protein synthesis but dependent on clathrin-mediated membrane trafficking. Together these results support the hypothesis that growth across the plant shoot system is balanced by competition between shoot apices for a common auxin transport path to the root and that strigolactones regulate shoot branching by modulating this competition.

Architecture & Planning2013Public Library of Science
Periodicals

The Solar Orbiter EUI instrument: The Extreme Ultraviolet Imager

Context. The Extreme Ultraviolet Imager (EUI) is part of the remote sensing instrument package of the ESA/NASA Solar Orbiter mission that will explore the inner heliosphere and observe the Sun from vantage points close to the Sun and out of the ecliptic. Solar Orbiter will advance the “connection science” between solar activity and the heliosphere. Aims. With EUI we aim to improve our understanding of the structure and dynamics of the solar atmosphere, globally as well as at high resolution, and from high solar latitude perspectives. Methods. The EUI consists of three telescopes, the Full Sun Imager and two High Resolution Imagers, which are optimised to image in Lyman- α and EUV (17.4 nm, 30.4 nm) to provide a coverage from chromosphere up to corona. The EUI is designed to cope with the strong constraints imposed by the Solar Orbiter mission characteristics. Limited telemetry availability is compensated by state-of-the-art image compression, onboard image processing, and event selection. The imposed power limitations and potentially harsh radiation environment necessitate the use of novel CMOS sensors. As the unobstructed field of view of the telescopes needs to protrude through the spacecraft’s heat shield, the apertures have been kept as small as possible, without compromising optical performance. This led to a systematic effort to optimise the throughput of every optical element and the reduction of noise levels in the sensor. Results. In this paper we review the design of the two elements of the EUI instrument: the Optical Bench System and the Common Electronic Box. Particular attention is also given to the onboard software, the intended operations, the ground software, and the foreseen data products. Conclusions. The EUI will bring unique science opportunities thanks to its specific design, its viewpoint, and to the planned synergies with the other Solar Orbiter instruments. In particular, we highlight science opportunities brought by the out-of-ecliptic vantage point of the solar poles, the high-resolution imaging of the high chromosphere and corona, and the connection to the outer corona as observed by coronagraphs.

Architecture & Planning2020EDP Sciences
Periodicals

Understanding nitrate assimilation and its regulation in microalgae

Nitrate assimilation is a key process for nitrogen (N) acquisition in green microalgae. Among Chlorophyte algae, Chlamydomonas reinhardtii has resulted to be a good model system to unravel important facts of this process, and has provided important insights for agriculturally relevant plants. In this work, the recent findings on nitrate transport, nitrate reduction and the regulation of nitrate assimilation are presented in this and several other algae. Latest data have shown nitric oxide (NO) as an important signal molecule in the transcriptional and posttranslational regulation of nitrate reductase and inorganic N transport. Participation of regulatory genes and proteins in positive and negative signaling of the pathway and the mechanisms involved in the regulation of nitrate assimilation, as well as those involved in Molybdenum cofactor synthesis required to nitrate assimilation, are critically reviewed.

Architecture & Planning2015Frontiers Media
Periodicals

Power System Resilience: Current Practices, Challenges, and Future Directions

The frequency of extreme events (e.g., hurricanes, earthquakes, and floods) and man-made attacks (cyber and physical attacks) has increased dramatically in recent years. These events have severely impacted power systems ranging from long outage times to major equipment (e.g., substations, transmission lines, and power plants) destructions. This calls for developing control and operation methods and planning strategies to improve grid resilience against such events. The first step toward this goal is to develop resilience metrics and evaluation methods to compare planning and operation alternatives and to provide techno-economic justifications for resilience enhancement. Although several power system resilience definitions, metrics, and evaluation methods have been proposed in the literature, they have not been universally accepted or standardized. This paper provides a comprehensive and critical review of current practices of power system resilience metrics and evaluation methods and discusses future directions and recommendations to contribute to the development of universally accepted and standardized definitions, metrics, evaluation methods, and enhancement strategies. This paper thoroughly examines the consensus on the power system resilience concept provided by different organizations and scholars and existing and currently practiced resilience enhancement methods. Research gaps, associated challenges, and potential solutions to existing limitations are also provided.

Architecture & Planning2020Institute of Electrical and Electronics Engineers
Periodicals

The Brand Relationship Spectrum

The purpose of brand positioning is to change the perception of prospective customers compared to other brands in the same product category. Many business organisations try to steer the customer's mind on the target brand and its advantage in the market. To determine whether the positioning of a certain brand is a success or not, a company should observe whether its brand is salient or not to the customers. Positioning or brand positioning includes choosing a particular product characteristic from the whole set of features associated with the brand. The main aim of this research is to determine the factors influencing the brand positioning of three-star hotels among residents in Kuala Terengganu. The first objective is to examine the relationship between the price and brand positioning of three-star hotels. The second objective is to determine the effect of brand image on the brand positioning of a three-star hotel. The third objective is to define the value of the brand positioning of a three-star hotel. The researcher disseminated 384 sets of questionnaires to 384 respondents in Kuala Terengganu and used SPSS version 20 to analyse the data. By using the data gathered, the researchers can produce frequency analysis, descriptive statistical analysis, Pearson test correlation analysis, regression analysis, hypothesis testing, and also the interpretation of objectives. The finding shows that two independent variables (price and brand image) have a significant relationship with the brand positioning of three stars hotels. Brand image is the vision of hotels in the industry more than what hotels' records show and the price represents the standard of service as perceived by the customers. Positioning is the use of marketing to project differentiation in the hotel and its services to targeted customers. Building and maintaining a strong brand positioning is critical in that it will help create a positive image and create unique perceptions among present and potential customers. A hotel with a positive brand positioning will transform a satisfied customer into loyal guests.

Architecture & Planning2000SAGE Publishing
Periodicals

Recent Advances in Pipeline Monitoring and Oil Leakage Detection Technologies: Principles and Approaches

Pipelines are widely used for the transportation of hydrocarbon fluids over millions of miles all over the world. The structures of the pipelines are designed to withstand several environmental loading conditions to ensure safe and reliable distribution from point of production to the shore or distribution depot. However, leaks in pipeline networks are one of the major causes of innumerable losses in pipeline operators and nature. Incidents of pipeline failure can result in serious ecological disasters, human casualties and financial loss. In order to avoid such menace and maintain safe and reliable pipeline infrastructure, substantial research efforts have been devoted to implementing pipeline leak detection and localisation using different approaches. This paper discusses pipeline leakage detection technologies and summarises the state-of-the-art achievements. Different leakage detection and localisation in pipeline systems are reviewed and their strengths and weaknesses are highlighted. Comparative performance analysis is performed to provide a guide in determining which leak detection method is appropriate for particular operating settings. In addition, research gaps and open issues for development of reliable pipeline leakage detection systems are discussed.

Architecture & Planning2019Multidisciplinary Digital Publishing Institute
Periodicals

Collective cell migration in morphogenesis and cancer

The movement of cells that maintain cell-cell junctions yet protrude along or within tissues is an important mechanism for cell positioning in morphogenesis, tissue repair and cancer. Collective cell migration shares similarities but also important differences to individually migrating cells. Coherent groups of cells are arranged and held together by cell-cell adhesion molecules, including cadherins, integrins, ALCAM and NCAM. Integrins of the beta 1 and beta 3 families further provide polarized interactions with the extracellular tissue environment, while matrix-degrading proteases become focalized to substrate contacts to widen tissue space for the advancing cell mass. By generating one functional unit, in contrast to individual cell migration, collective migration provides the active and passive translocation of mobile and non-mobile cells, respectively. This review highlights cellular and molecular principles of collective migration in the context of morphogenic tissue patterning and tumor cell invasion.

Architecture & Planning2004University of the Basque Country
Periodicals

Mechanisms Regulating the Dynamics of Photosynthesis Under Abiotic Stresses

Photosynthesis sustains plant life on earth and is indispensable for plant growth and development. Factors such as unfavorable environmental conditions, stress regulatory networks, and plant biochemical processes limits the photosynthetic efficiency of plants and thereby threaten food security worldwide. Although numerous physiological approaches have been used to assess the performance of key photosynthetic components and their stress responses, though, these approaches are not extensive enough and do not favor strategic improvement of photosynthesis under abiotic stresses. The decline in photosynthetic capacity of plants due to these stresses is directly associated with reduction in yield. Therefore, a detailed information of the plant responses and better understanding of the photosynthetic machinery could help in developing new crop plants with higher yield even under stressed environments. Interestingly, cracking of signaling and metabolic pathways, identification of some key regulatory elements, characterization of potential genes, and phytohormone responses to abiotic factors have advanced our knowledge related to photosynthesis. However, our understanding of dynamic modulation of photosynthesis under dramatically fluctuating natural environments remains limited. Here, we provide a detailed overview of the research conducted on photosynthesis to date, and highlight the abiotic stress factors (heat, salinity, drought, high light, and heavy metal) that limit the performance of the photosynthetic machinery. Further, we reviewed the role of transcription factor genes and various enzymes involved in the process of photosynthesis under abiotic stresses. Finally, we discussed the recent progress in the field of biodegradable compounds, such as chitosan and humic acid, and the effect of melatonin (bio-stimulant) on photosynthetic activity. Based on our gathered researched data set, the logical concept of photosynthetic regulation under abiotic stresses along with improvement strategies will expand and surely accelerate the development of stress tolerance mechanisms, wider adaptability, higher survival rate, and yield potential of plant species.

Architecture & Planning2021Frontiers Media